12. tbl. 102. árg. 2016

Results of operations for ascending aortic aneurysm in Iceland 2000-2014

Árangur aðgerða við ósæðargúlp í rishluta ósæðar á Íslandi 2000-2014


Introduction: Thoracic aortic aneurysm (TAA) is an uncommon disease where treatment is complex and associated with significant comorbidity. The main aim of this study was to evaluate the outcomes of operations for TAA in Iceland with emphasis on postoperative complications, 30 day mortality and survival.

Materials and methods: A retrospective study on 105 patients (mean age 60.7 yrs., 69.5% males) that underwent operations for TAA between 2000 and 2014 in Iceland. Patients with aortic injury or acute aortic dissection were excluded. Clinical information was collected from hospital charts and long-term survival estimated by Kaplan-Meier method. Mean follow-up was 5.7 yrs.

Results: Bicuspid aortic valve was present in 52 patients (51.0%) and family history was positive in 10 of the cases (9.5%). Every other patient (50.5%) was asymptomatic and diagnosed incidentally. The most common procedure was aortic root replacement using biological prosthesis. Two out of three patients had complications, that were regarded as major in 31.4% of cases, however,  stroke was only detected in 2 (1.9%) patients. Two patients died within 30 days postoperatively (1.9%). The overall survival at one year was 95.1%; more favorable for males compared to females (97.2 vs. 90.4%, p=0.0012, log rank test) and at 5 years 90.3%.

Conclusions: Outcome following surgery for TAA in Iceland is comparable to studies in neighbouring countries. The complications rate is high, however, the stroke rate was low, as was 30 day mortality.  Longterm survival is favorable, and is more favorable for males than females.

Table I. Demographics. Number and ratio (%) or mean with standard deviation. N=105.

Table II. Operative variables. Number and ratio (%) or mean with standard deviation N=105.

Table III. Postoperative complications. Number and ratio (%). N=105.

Table IV. Bleeding and use of blood components. Mean with standard deviation and range. N=105.


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