Fræðigrein

Pulmonary sequestration (PS) is a rare disease where non-functioning lung tissue is separated from the normal bronchopulmonary tree and vasularized by an aberrant systemic artery. The origin of PS is not fully understood. Here we describe two unique cases of PS that support the hypothesis that PS is a congenital malformation rather than an aquired one. These are also the first Icelandic cases of PS reported.

Correspondence: Tómas Guðbjartsson, tomasgudbjartsson@hotmail.com

 

 

 

Figure 1. A unique bronchogram (large arrow) after gastrography in Case A . The contrast can be traced from the gastro-oesophagal junction to the pulmonary sequestration (small arrow) in the right hemithorax[s1] .

 

Figure 2. Angiography of Case A demonstrating the large caliber of the abberant artery (arrow[N2] ).

 

Figure 3. Computed tomgraphy scan with an infiltration in the right lung in Case B. Between the infiltration and oesophagus there is a fluid fylled cyst.

 

Figure 4. Histology from the pulmonary sequestration in Case B. A). A bronchus-like structure close to the cyst is lined with respiratory epithelium, the wall containing hyaline cartilage, seromucous glands and several medium sized abnormal vessels. B). Histology of the cyst wall resembles that of the oesophagus, with inner surface lined with a squamous epithelium above a thin muscularis mucosae. In a thick muscularis propria there are two layers of smooth muscle.